Search results for " loading"

showing 10 items of 157 documents

Positive effect of platelet rich fibrin on osseointegration

2016

Background Leukocyte-platelet rich fibrin (L-PRF) is a second generation platelet concentrate clinically used to accelerate tissue healing and bone regeneration. Achieving reduced implant osseointegration time could provide immediate or early loading of implants. The aim of this study was to evaluate the L-PRF-induced osseointegration and bone-implant contact (BIC) in an experimental animal model. Material and Methods Twelve 4-month-old New Zealand white rabbits were used. Following general anesthesia, 3-5 mL of blood was obtained from the central artery in rabbit ear and L-PRF was prepared. Two implant cavities (5 mm long and 3 mm in diameter) were created in each tibia with a total of fou…

0106 biological sciencesBone RegenerationDentistry01 natural sciencesOsseointegrationFibrin03 medical and health sciences0302 clinical medicineOsseointegrationPlatelet-Rich Fibrin010608 biotechnologyEarly loadingAnimalsMedicinePlatelet concentrateBone regenerationMatrix for growth factorsGeneral DentistryDental ImplantsFibrinbiologybusiness.industryResearch030206 dentistry:CIENCIAS MÉDICAS [UNESCO]digestive system diseasesPlatelet-rich fibrinExperimental animalOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASbiology.proteinSurgeryRabbitsImplantOral SurgerybusinessPlatelet rich fibrinMedicina Oral Patología Oral y Cirugia Bucal
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Food load manipulation ability shapes flight morphology in females of central-place foraging Hymenoptera

2013

Received: 19 March 2013.- Accepted: 20 June 2013.- Published: 28 June 2013

0106 biological sciencesForagingWaspsBiodiversityHymenopteraBiologyDevelopment010603 evolutionary biology01 natural sciencesPredation03 medical and health sciencesWing loadingForagingCoevolutionEcology Evolution Behavior and Systematics030304 developmental biology0303 health sciencesNatural selectionEcologyResearchFlight Muscle RatioBeesbiology.organism_classificationLower wingWing LoadingAnimal Science and ZoologyFrontiers in Zoology
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Impact loading history modulates hip fracture load and location : A finite element simulation study of the proximal femur in female athletes

2018

Sideways falls impose high stress on the thin superolateral cortical bone of the femoral neck, the region regarded as a fracture-prone region of the hip. Exercise training is a natural mode of mechanical loading to make bone more robust. Exercise-induced adaptation of cortical bone along the femoral neck has been previously demonstrated. However, it is unknown whether this adaption modulates hip fracture behavior. The purpose of this study was to investigate the influence of specific exercise loading history on fall-induced hip fracture behavior by estimating fracture load and location with proximal femur finite element (FE) models created from magnetic resonance images (MRI) of 111 women w…

02 engineering and technologyFinite element simulationWeight-Bearing0302 clinical medicinemurtumatreisiluuOrthopedics and Sports MedicineFemurOrthodonticsHip fractureluustomedicine.diagnostic_testbiologyProximal femurexerciseRehabilitationfallingfemoral neckta3142lonkkamurtumatBiomechanical Phenomenamedicine.anatomical_structureFemalevahvistaminenAdultFinite Element Analysis0206 medical engineeringBiomedical EngineeringBiophysics030209 endocrinology & metabolismbone strengthYoung Adult03 medical and health sciencesmedicineHumansFemoral neckHip Fracturesbusiness.industryAthletesMagnetic resonance imagingfinite element modelingmedicine.diseasebiology.organism_classification020601 biomedical engineeringAthletesImpact loadingAccidental FallsCortical bonebusinesshuman activitiesJournal of Biomechanics
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On the estimation of the fatigue cycle distribution from spectral density data

1999

This paper deals with the fatigue life prediction of components and structures subjected to random fatigue, i.e. to cyclic loading whose amplitude varies in an essentially random manner. In particular, this study concentrates on the general problem of directly relating fatigue cycle distribution to the power spectral density (PSD) by means of closed-form expressions that avoid expensive digital simulations of the stress process. At present, all the methods proposed to achieve this objective are based on the use of a single parameter of the PSD. In this work, by numerical simulations and theoretical considerations, it is shown that the statistical distribution of fatigue cycles depends on f…

0209 industrial biotechnologyStochastic processMechanical EngineeringMathematical analysisSpectral density02 engineering and technologyNarrow band020303 mechanical engineering & transports020901 industrial engineering & automationDistribution (mathematics)Amplitude0203 mechanical engineeringCalculusCyclic loadingClosed-form expressionMathematicsVibration fatigueProceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science
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Population pharmacokinetic meta-analysis of individual data to design the first randomized efficacy trial of vancomycin in neonates and young infants.

2019

Abstract Objectives In the absence of consensus, the present meta-analysis was performed to determine an optimal dosing regimen of vancomycin for neonates. Methods A ‘meta-model’ with 4894 concentrations from 1631 neonates was built using NONMEM, and Monte Carlo simulations were performed to design an optimal intermittent infusion, aiming to reach a target AUC0–24 of 400 mg·h/L at steady-state in at least 80% of neonates. Results A two-compartment model best fitted the data. Current weight, postmenstrual age (PMA) and serum creatinine were the significant covariates for CL. After model validation, simulations showed that a loading dose (25 mg/kg) and a maintenance dose (15 mg/kg q12h if &lt…

0301 basic medicinePediatricsvancomycininfusion procedures0302 clinical medicinenewbornMedicinePharmacology (medical)Randomized Controlled Trials as Topiceducation.field_of_studyMaintenance doseAnti-Bacterial Agents3. Good healthInfectious Diseasesdrug maintenance doseResearch DesignArea Under CurveData Interpretation Statisticalcreatinine testsVancomycinMonte Carlo Methodmedicine.drugMicrobiology (medical)medicine.medical_specialty030106 microbiologyPopulationGestational AgeMicrobial Sensitivity TestsLoading doseRS03 medical and health sciencesPharmacokineticsdrug loading dose030225 pediatricsHumanssteady stateeducationPharmacologyDose-Response Relationship Drugbusiness.industryBody WeightInfant NewbornPostmenstrual AgeinfantNONMEMRegimen[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologieregimen[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiebusinessserum
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Bone loss around narrow implants versus standard diameter implants: Retrospective 2-years case-control study

2019

Background The objectives were to evaluate the bone loss (BL) around narrow diameter implants (3.3 mm) 2 years after implant loading and compare with the bone loss around conventional-diameter implants (4.1 mm), as well as with clinical and anatomical variables. 2-years follow-up. Material and Methods Cases: 20 patients either gender-age, narrow implants (Straumann TM-SLA, diameter 3.3 mm); Control: 20 patients matching for gender-age, conventional implants (Straumann TM-SLA, diameter 4.1). Total 82 implants (31 narrow implants and 51 conventional implants) in 40 patients. To avoid statistical bias, a cluster of one implant per patient was randomly selected (20 narrow implants and 20 conven…

0303 health sciencesProsthetic DentistryTobacco useClinical variablesPost hocbusiness.industryRadiographyResearchDentistry030206 dentistry:CIENCIAS MÉDICAS [UNESCO]03 medical and health sciences0302 clinical medicineStatistical significanceUNESCO::CIENCIAS MÉDICASMedicineImplantImplant loadingbusinessGeneral Dentistry030304 developmental biologyJournal of Clinical and Experimental Dentistry
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Osseotite caricati a due mesi nei settori posteriori del mascellare superiore: controllo a 2 anni di due casi clinici

2003

Aim Acid etched surface implants determine high clinical success rates, but little information is available about early loading in the posterior region of the maxilla, area at risk of failure. The aim of this work is to present two case reports of oral rehabilitation through acid etched surface implants (Osseotite, Implant Innovations - 3i, West Palm Beach, FL) loaded two months after insertion in the posterior maxilla. Materials and methods The success of Osseotite implants was assessed 12 and 24 months after prosthetic loading according to Albrektsson et al. criteria (1986). Results No clinical or radiographic signs of implant failure were observed during the two years follow-up. Conclusi…

Acid-etched surfaces early loading posterior maxilla
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Foot Strike Pattern, Step Rate, and Trunk Posture Combined Gait Modifications to Reduce Impact Loading during Running

2019

Elevated impact loading can be detrimental to runners as it has been linked to the increased risk of tibial stress fracture and plantar fasciitis. The objective of this study was to investigate the combined effects of foot strike pattern, step rate, and anterior trunk lean gait modifications on impact loading in runners. Nineteen healthy runners performed 12 separate gait modification trials involving: three foot strike patterns (rearfoot, midfoot, and forefoot strike), two step rates (natural and 10% increased), and two anterior trunk lean postures (natural and 10-degree increased flexion). Overall, forefoot strike combined with increased step rate led to the lowest impact loading rates, a…

AdultMaleFoot strikelanding patternmedicine.medical_specialtyFractures Stress0206 medical engineeringBiomedical EngineeringBiophysicsPlantar fasciitis02 engineering and technologyRunningjuoksu03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationGait (human)medicineHumansOrthopedics and Sports MedicineRange of Motion ArticularTrunk postureta315GaitpostureryhtiFootbusiness.industryForefootRehabilitationvertical loadingTorso020601 biomedical engineeringTrunkBiomechanical PhenomenaTibial Fracturesbody regionsImpact loadingFemalecadencebiomekaniikkamedicine.symptombusinessCadencehuman activities030217 neurology & neurosurgerydistance runnersJournal of Biomechanics
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Maintenance of marginal bone support and soft tissue esthetics at immediately provisionalized OsseoSpeed implants placed into extraction sites: 2-yea…

2012

Background Placement of implants into extraction sockets targets the maintenance of peri-implant hard and soft tissue structures and the support of a natural and esthetic contour. The main advantages of immediate implant insertion in comparison with delayed implant placement protocols are as follows: a reduced treatment time, less number of sessions, and, thus, the less invasive procedure. This study examines the clinical performance (survival rate, marginal bone levels and Pink Esthetic Score [PES]) of OsseoSpeed™ implants placed into extraction sockets with immediate provisionalization in the anterior maxilla after a follow-up of at least 12 months. Methods Twenty patients received a tota…

AdultMaleImmediate Dental Implant LoadingFacial boneEstheticsmedicine.medical_treatmentAlveolar Bone LossDentistryProsthesisDental Implants Single-ToothAlveolar ProcessMedicineHumansProspective StudiesTooth SocketSurvival rateAgedbusiness.industryAlveolar processClinical performanceSoft tissueMiddle AgedImmediate provisionalizationmedicine.anatomical_structureTreatment OutcomeDental Prosthesis DesignFemaleImplantOral SurgerybusinessClinical oral implants research
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Clinical and esthetic outcome with immediate insertion and provisionalization with or without connective tissue grafting in presence of mucogingival …

2017

Background Recessions following immediate implant insertion are frequently reported in the literature. Data regarding implant installation in presence of mucogingival recessions are rare. Purpose This study observes soft tissue level changes following immediate implant insertion and provisionalization of implants with or without connective tissue grafts in the anterior maxilla in patients with initial mucogingival recession within a follow-up period between one and eight years. Materials and methods Twenty-six patients with marginal gingival recessions, which were designated for extraction and immediate implant insertion in the anterior zone of the maxilla (13-23), were included. Out of a l…

AdultMaleImmediate Dental Implant LoadingFacial boneGingivaDentistryConnective tissueEsthetics DentalTransplantation AutologousYoung Adult03 medical and health sciencesDental Implants Single-Tooth0302 clinical medicineGermanyMaxillaRetrospective analysisHumansPeriodontal PocketMedicineGingival RecessionGeneral DentistryAgedRetrospective StudiesDental ImplantsBone Transplantationbusiness.industrySoft tissue030206 dentistrySingle toothCone-Beam Computed TomographyMiddle AgedAutologous boneIncisorTreatment Outcomemedicine.anatomical_structureDental Prosthesis DesignConnective Tissue030220 oncology & carcinogenesisMaxillaTooth ExtractionFemaleDental Prosthesis Implant-SupportedImplantOral SurgerybusinessFollow-Up StudiesClinical Implant Dentistry and Related Research
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