Search results for "D.0"
showing 10 items of 11671 documents
Circular RNA in Exosomes
2018
Circular RNAs (circRNAs) are a novel family of non-coding endogenous RNAs discovered in all eukaryotic cells and generated through a particular mechanism of alternative splicing called “back-splicing”. These molecules show multiple functions, by acting as modulators of gene and miRNA expression, and may have a role in several biological processes, such as cell proliferation and invasion with, tumour development and progression, and in several mechanisms underlying other diseases. Their presence has been shown to be abundant in several body fluids such as blood and saliva. Based on their biogenesis mechanism, cir- cRNAs may be categorized into five classes: exonic circRNAs, intronic circRNAs…
Structure, morphology and photoluminescence emissions of ZnMoO4: RE 3+=Tb3+ - Tm3+ - X Eu3+ (x = 1, 1.5, 2, 2.5 and 3 mol%) particles obtained by the…
2018
Made available in DSpace on 2018-12-11T17:36:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-06-25 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Ministerio de Economía y Competitividad ZnMoO4 and ZnMoO4: RE3+ = 1% Tb3+, 1% Tm3+, x Eu3+ (x = 1, 1.5, 2, 2.5 and 3 mol%) particles were prepared by a sonochemical method. The influence of the dopant content on photoluminescent behavior was investigated. The X-ray diffraction results confirmed the formation of the α-ZnMoO4 phase with a triclinic crystalline structure. The influence of th…
Prevalence and characteristics of antidepressant drug prescriptions in older Italian patients.
2012
ABSTRACTBackground: During last few decades, the proportion of elderly persons prescribed with antidepressants for the treatment of depression and anxiety has increased. The aim of this study was to evaluate prevalence of antidepressant prescription and related factors in elderly in-patients, as well as the consistency between prescription of antidepressants and specific diagnoses requiring these medications.Methods: Thirty-four internal medicine and four geriatric wards in Italy participated in the Registro Politerapie SIMI–REPOSI study during 2008. In all, 1,155 in-patients, 65 years or older, were enrolled. Prevalence of the use of antidepressants was calculated at both admission and dis…
Association between clusters of diseases and polypharmacy in hospitalized elderly patients: results from the REPOSI study.
2011
BACKGROUND: Although the association between multimorbidity and polypharmacy has been clearly documented, no study has analyzed whether or not specific combinations of diseases influence the prescription of polypharmacy in older persons. We assessed which clusters of diseases are associated with polypharmacy in acute-care elderly in-patients. METHODS: This cross-sectional study was held in 38 Italian internal medicine and geriatric wards participating in the Registro Politerapie SIMI (REPOSI) study during 2008. The study sample included 1155 in-patients aged 65 years or older. Clusters of diseases, defined as two or more co-occurring specific chronic diseases, were identified using the odds…
Performance of PSI, CURB-65, and SCAP scores in predicting the outcome of patients with community-acquired and healthcare-associated pneumonia
2011
The objective was to compare three score systems, pneumonia severity index (PSI), the Confusion-Urea-Respiratory Rate-Blood pressure-65 (CURB-65), and severe community-acquired pneumonia (SCAP), for prediction of the outcomes in a cohort of patients with community-acquired (CAP) and healthcare-associated pneumonia (HCAP). Large multi-center, prospective, observational study was conducted in 55 hospitals. HCAP patients were included in the high classes of CURB-65, PSI and SCAP scores have a mortality rate higher than that of CAP patients. HCAP patients included in the low class of the three severity rules have a significantly higher incidence of adverse events, including development of septi…
The impact of quantitative easing on UK bank lending: Why banks do not lend to businesses?
2021
Abstract The growing proportion of UK bank lending to the financial sector reached a peak in 2007 just before the onset of the Global Financial Crisis (GFC). This marks a trend in the dwindling amount of bank lending to private sector non-financial corporations (PNFCs), which was exacerbated with the Great Recession. Many central banks aimed to revive bank lending with quantitative easing (QE) and unconventional monetary policy. We propose an agent based computational economics (ACE) model which combines the main factors in the economic environment of QE and Basel regulatory framework to analyse why UK banks do not prioritize lending to non-financial businesses. The lower bond yields caused…
Une structure o-minimale sans décomposition cellulaire
2008
Resume Nous construisons une extension o-minimale du corps des nombres reels qui n'admet pas la propriete de decomposition cellulaire en classe C ∞ . Pour citer cet article : O. Le Gal, J.-P. Rolin, C. R. Acad. Sci. Paris, Ser. I 346 (2008).
Partially hyperbolic diffeomorphisms with a uniformly compact center foliation: the quotient dynamics
2016
We show that a partially hyperbolic$C^{1}$-diffeomorphism$f:M\rightarrow M$with a uniformly compact$f$-invariant center foliation${\mathcal{F}}^{c}$is dynamically coherent. Further, the induced homeomorphism$F:M/{\mathcal{F}}^{c}\rightarrow M/{\mathcal{F}}^{c}$on the quotient space of the center foliation has the shadowing property, i.e. for every${\it\epsilon}>0$there exists${\it\delta}>0$such that every${\it\delta}$-pseudo-orbit of center leaves is${\it\epsilon}$-shadowed by an orbit of center leaves. Although the shadowing orbit is not necessarily unique, we prove the density of periodic center leaves inside the chain recurrent set of the quotient dynamics. Other interesting proper…
Inverse estimation of model parameters for newborn brain cooling process simulations
2019
In this work, a three-dimensional simplified computational model was built to simulate the passive thermo-physiological response of part of a newborn’s head for neonate’s selective brain cooling. Both metabolicheat generation and blood perfusion were considered. The set of model parameters was selected anda sensitivity study was carried out. Analysis of dimensionless sensitivity coefficients showed that the mostimportant are: the contact thermal resistance between the cool-cap and skin, the thermal resistance ofthe plastic wall material, and deep (arterial) blood temperature. The function specification method wasapplied to estimate the value of the contact resistance. Two, four and six comp…
Efficient generation of restricted growth words
2013
A length n restricted growth word is a word w=w"1w"2...w"n over the set of integers where w"1=0 and each w"i, i>1, lies between 0 and the value of a word statistics of the prefix w"1w"2...w"i"-"1 of w, plus one. Restricted growth words simultaneously generalize combinatorial objects as restricted growth functions, staircase words and ascent or binary sequences. Here we give a generic generating algorithm for restricted growth words. It produces a Gray code and runs in constant average time provided that the corresponding statistics has some local properties.