Search results for "Metal interaction"
showing 4 items of 4 documents
Deregulated High Affinity Copper Transport Alters Iron Homeostasis inArabidopsis
2020
The present work describes the effects on iron homeostasis when copper transport was deregulated in Arabidopsis thaliana by overexpressing high affinity copper transporters COPT1 and COPT3 (COPTOE). A genome-wide analysis conducted on COPT1OE plants, highlighted that iron homeostasis gene expression was affected under both copper deficiency and excess. Among the altered genes were those encoding the iron uptake machinery and their transcriptional regulators. Subsequently, COPTOE seedlings contained less iron and were more sensitive than controls to iron deficiency. The deregulation of copper (I) uptake hindered the transcriptional activation of the subgroup Ib of basic helix-loop-helix (bHL…
Investigating the emerging role of comparative proteomics in the search for new biomarkers of metal contamination under varying abiotic conditions
2016
13 pages; International audience; This study aims at investigating the potential use of comparative proteomics as a multi-marker approach of metal contamination, taking into account the potential confounding effect of water temperature. The major objective was to identify combinations of proteins specifically responding to a given metal, even if included in a metal mixture. The diagnostic approach was performed via the comparative analysis of protein expression on spot mapping provided by adult males of Gammarus pulex (Amphipoda, Crustacea) respectively exposed to arsenate (As), cadmium (Cd) or a binary mixture of these metals (AsCd) at three realistic temperatures (5, 10 and 15 °C). Proteo…
Thermal-hydraulic and thermo-mechanical simulations of Water-Heavy Liquid Metal interactions towards the DEMO WCLL breeding blanket design
2019
Abstract The Water-Cooled Lithium Lead breeding blanket concept foresees the eutectic lithium-lead (Pb-15.7Li) alloy being cooled by pressurized sub-cooled water (temperature 295–328 °C; pressure 15.5 MPa) flowing in double wall tubes. Therefore, the interaction between the Pb-15.7Li and water (e.g. tube rupture) represents one of the main safety concerns for the design and safety analysis. Available LIFUS5/Mod2 experimental data are employed to assess the performances of thermal-hydraulic and thermo-mechanic codes. Thermal-hydraulic simulations, by SIMMER-III code, are focused on the prediction of the thermodynamic interaction among the fluids. ABAQUS Finite Element code, used for the desi…