Search results for "NDM-1"

showing 2 items of 2 documents

Characterization of Carbapenem-Resistant Enterobacteriaceae Clinical Isolates in Al Thawra University Hospital, Sana'a, Yemen

2020

International audience; Objective: The aim of this study was to investigate the resistance mechanisms of carbapenem-resistant Enterobacteriaceae clinical strains recovered from Al Thawra University Hospital, Sana'a, Yemen. Methods: A total of 27 isolates showing decreased susceptibility to carbapenems were obtained from different clinical specimens in Al Thawra Hospital, Sana'a, Yemen. Strains were identified by Matrix Assisted Laser Desorption Ionization Time-Of-Flight spectroscopy. Susceptibility to antibiotics was determined by the disk diffusion method on Mueller Hinton agar. Carbapenemases-encoding genes, extended-spectrum β-lactamases (ESBLs), and plasmid-mediated quinolone resistance…

MaleYemenKlebsiella pneumoniaeGene ExpressionCarbapenem-resistant enterobacteriaceaeQuinolonesmedicine.disease_causeHospitals Universitychemistry.chemical_compoundChildEscherichia coli InfectionsAged 80 and over0303 health sciencesbiologyEnterobacteriaceae InfectionsMiddle AgedEnterobacteriaceae3. Good healthAnti-Bacterial AgentsBacterial Typing TechniquesMueller-Hinton agarKlebsiella pneumoniae[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyNDM-1-likeChild PreschoolFemalePlasmidsMicrobiology (medical)AdultcarbapenemasesImmunologyMicrobial Sensitivity TestsMicrobiologybeta-Lactam Resistancebeta-LactamasesMicrobiology03 medical and health sciencesEnterobacteriaceaeEnterobacter cloacaemedicineEscherichia coliHumansTypingEscherichia coli030304 developmental biologyAgedPharmacology030306 microbiologyInfantbiochemical phenomena metabolism and nutritionbiology.organism_classificationClone CellsKlebsiella InfectionsCarbapenem-Resistant EnterobacteriaceaechemistryCarbapenemsMultilocus sequence typingbacteriaEnterobacter cloacaeMultilocus Sequence TypingOXA-48-like
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NDM-1 and OXA-163 producing Klebsiella pneumoniae isolates in Cairo, Egypt, 2012

2013

Here we describe carbapenem resistance determinants in two Klebsiella pneumoniae isolates recovered from two hospitalised patients in the same intensive care unit of a cancer hospital in Cairo, Egypt. PCR and sequencing were used to detect and characterise β-lactamase genes. Clonal relationships between the isolates were analysed by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). The first K. pneumoniae isolate carried the blaNDM-1 gene and the second isolate carried the blaOXA-163 gene. Both isolates co-expressed the extended-spectrum β-lactamase CTX-M-15. The two isolates belonged to different sequence types (STs), ST11 and ST16, respectively. No history of …

Microbiology (medical)Antimicrobial drug resistanceSettore MED/07 - Microbiologia E Microbiologia ClinicaOXA-163biologyGeographic areaKlebsiella pneumoniaeImmunologyNorth africaSequence typesNDM-1biology.organism_classificationMicrobiologyVirologyMicrobiologyCarbapenemaseKlebsiella pneumoniaeNDM-1; OXA-163; Carbapenemase; Klebsiella pneumoniae; Antimicrobial drug resistancePulsed-field gel electrophoresisImmunology and AllergyMultilocus sequence typingCarbapenem resistance
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